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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.81762195 |
| Normalized Enrichment Score (NES) | -1.7135992 |
| Nominal p-value | 0.0021231424 |
| FDR q-value | 0.02439854 |
| FWER p-Value | 0.022 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK8 | 6459 | 2251 | 0.267 | -0.1043 | No | ||
| 2 | MAP2K1 | 19082 | 2640 | 0.166 | -0.1146 | No | ||
| 3 | MAP2K2 | 19933 | 3325 | 0.072 | -0.1468 | No | ||
| 4 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 3347 | 0.070 | -0.1435 | No | ||
| 5 | AKT1 | 8568 | 4202 | 0.032 | -0.1875 | No | ||
| 6 | KIT | 16823 | 4403 | 0.027 | -0.1965 | No | ||
| 7 | SPRED2 | 8539 4332 | 4436 | 0.027 | -0.1965 | No | ||
| 8 | SHC1 | 9813 9812 5430 | 4437 | 0.027 | -0.1948 | No | ||
| 9 | STAT5A | 20664 | 4526 | 0.025 | -0.1979 | No | ||
| 10 | HRAS | 4868 | 4722 | 0.022 | -0.2070 | No | ||
| 11 | PTPRO | 1093 17256 | 4749 | 0.022 | -0.2070 | No | ||
| 12 | MATK | 3425 19930 | 5426 | 0.015 | -0.2425 | No | ||
| 13 | SNAI2 | 22848 | 6674 | 0.008 | -0.3092 | No | ||
| 14 | GRB10 | 4799 | 6979 | 0.007 | -0.3251 | No | ||
| 15 | EPO | 8911 | 7000 | 0.007 | -0.3257 | No | ||
| 16 | GRAP2 | 5113 9398 | 7078 | 0.006 | -0.3295 | No | ||
| 17 | LYN | 16281 | 9749 | -0.001 | -0.4732 | No | ||
| 18 | KITLG | 19889 3342 | 10459 | -0.002 | -0.5113 | No | ||
| 19 | DOK1 | 17104 1018 1177 | 10626 | -0.003 | -0.5200 | No | ||
| 20 | SOS1 | 5476 | 10751 | -0.003 | -0.5265 | No | ||
| 21 | PIK3R1 | 3170 | 11690 | -0.006 | -0.5766 | No | ||
| 22 | MITF | 17349 | 11764 | -0.006 | -0.5802 | No | ||
| 23 | CBL | 19154 | 11840 | -0.006 | -0.5838 | No | ||
| 24 | PTPN11 | 5326 16391 9660 | 12084 | -0.007 | -0.5964 | No | ||
| 25 | FOXO3 | 19782 3402 | 13423 | -0.015 | -0.6675 | No | ||
| 26 | EPOR | 19204 | 13635 | -0.017 | -0.6778 | No | ||
| 27 | PIK3CA | 9562 | 13925 | -0.021 | -0.6920 | No | ||
| 28 | JAK2 | 23893 9197 3706 | 14328 | -0.027 | -0.7120 | No | ||
| 29 | SPRED1 | 4331 | 14919 | -0.044 | -0.7410 | No | ||
| 30 | RPS6KB1 | 7815 1207 13040 | 15086 | -0.051 | -0.7467 | No | ||
| 31 | SH2B3 | 5001 16383 | 15241 | -0.058 | -0.7513 | No | ||
| 32 | RAF1 | 17035 | 16474 | -0.248 | -0.8019 | Yes | ||
| 33 | MAP4K1 | 18313 | 16669 | -0.306 | -0.7929 | Yes | ||
| 34 | TEC | 16514 | 16770 | -0.340 | -0.7767 | Yes | ||
| 35 | GRB2 | 20149 | 16888 | -0.389 | -0.7583 | Yes | ||
| 36 | MAPK3 | 6458 11170 | 17011 | -0.437 | -0.7371 | Yes | ||
| 37 | GSK3B | 22761 | 17503 | -0.658 | -0.7218 | Yes | ||
| 38 | BAD | 24000 | 17587 | -0.709 | -0.6812 | Yes | ||
| 39 | CREBBP | 22682 8783 | 17641 | -0.746 | -0.6366 | Yes | ||
| 40 | SOCS1 | 4522 | 17684 | -0.779 | -0.5894 | Yes | ||
| 41 | CRKL | 4560 | 17704 | -0.794 | -0.5400 | Yes | ||
| 42 | VAV1 | 23173 | 17823 | -0.886 | -0.4901 | Yes | ||
| 43 | PTEN | 5305 | 18041 | -1.135 | -0.4297 | Yes | ||
| 44 | PDPK1 | 23097 | 18082 | -1.189 | -0.3563 | Yes | ||
| 45 | GAB1 | 18828 | 18157 | -1.275 | -0.2793 | Yes | ||
| 46 | STAT1 | 3936 5524 | 18185 | -1.330 | -0.1962 | Yes | ||
| 47 | STAT3 | 5525 9906 | 18210 | -1.378 | -0.1100 | Yes | ||
| 48 | PTPN6 | 17002 | 18450 | -2.074 | 0.0089 | Yes |
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